N N Dimethylglycine Dmg



DMG: An All-Natural Wellness Builder

The concentration of N,N-dimethylglycine (DMG) was increased approximately 100-fold in serum and 20-fold in urine. The presence of DMG as a storage product was confirmed by use of NMR spectroscopy and gas chromatography-mass spectrometry. The high concentration of DMG was caused by a deficiency of the enzyme dimethylglycine dehydrogenase. DMG (dimethylglycine) is a dimethylated derivative of the simple amino acid glycine. It improves oxygen utilization and may act as an antioxidant by stimulating lymphocyte proliferation and interferon production. Research suggests that DMG, also known as N, N-Dimethylglycine, is an essential nutrient to cellular metabolism, brain function, immune system function and even nerve transmission. Cautions: Pregnant or nursing women should consult their physician before using. Keep out of the reach of children. Store in a cool, dry place with lid tightly closed.


by Roger V. Kendall, Ph.D.
Dimethylglycine (DMG) is a relatively small molecule with an amazing power to change and improve health, well-being, and vitality in a person's life.
A natural substance found in certain foods like meat (liver), beans, seeds, and grains, DMG is an intermediary metabolite—meaning it is rapidly broken down into other useful substances your body requires. DMG, which affects many metabolic pathways within the cell, is also produced in small amounts by humans and animals. Officially named N, N-Dimethylglycine, DMG is related to the amino acid, glycine, whose two hydrogen atoms have been replaced with methyl (CH3) groups on its nitrogen atom. Research shows it to be physiologically active and important to cell metabolism, as well as a supplier of essential methyl groups for modifying, building, and detoxifying many components in the body.
Over 25 years of research and clinical studies have demonstrated DMG, as a nutritional supplement, has many positive effects, including stress reduction, improved athletic and sexual performance, and enhanced cardiovascular, brain, and immune functions. An adaptogen, DMG works with other co-factors in the body to counteract the negative effects of physical, emotional, and metabolic stress and to help prevent and overcome degenerative diseases. It can also normalize physiological functions and help maintain homeostasis (balance) within the body. These physiological functions include the regulation of blood glucose levels, immune response, blood pressure, hypoxic or low-oxygen conditions, hormone and cholesterol levels, as well as those of important biologically active molecules like SAMe, glutathione, and creatine.
Studies also show DMG:
  • Provides useful building blocks for the biosynthesis of vitamins, hormones, neurotransmitters, antibodies, nucleic acids, and other metabolically active molecules
  • Supports all aspects of immune response by acting as an anti-viral, anti-bacterial, and anti-fungal agent
  • Promotes cardiovascular functions by supporting normal triglyceride and cholesterol levels, reducing angina, improving circulation, and decreasing elevated homocysteine levels
  • Improves oxygenation, thus reducing fatigue and increasing energy for improved physical and mental performance
  • Supports neurological function and mental clarity by acting as a precursor to the amino acids that are building blocks for neurotransmitters
  • Acts as an antioxidant against free radicals
  • Supports detoxification and enhances liver function, particularly Phase II detoxification (the phase that excretes converted toxic metabolites)
One reason DMG affects so many areas in the body is because it contributes to methylation, a biochemical process essential to life and necessary for good health. Through trans-methylation (the transfer of a methyl group from one molecule to another), DMG supplies methyl groups for many of the modifying, building, detoxifying, recycling, activating, and protecting reactions that change the structure and function of many components in the body. As a source of methyl groups, DMG causes certain critical chemical reactions to proceed more efficiently. Specifically, DMG recycles SAMe, the primary methyl donor in the body, which helps lower elevated homocysteine, an identified risk factor in cardiovascular disease. Through the methyl donor SAMe, DMG supports nerve function and neurotransmitter production, improves verbal communication, social behavior, and sleep patterns of autistic children. DMG also functions as a mineral transporter, chelating agent, and cell communicator. DMG helps detoxify toxic substances via its effect on Phase II detoxification by the liver. Methyl groups are attached to toxic metabolites to produce new water-soluble, readilyexcreted compounds.
Depending on the specific health problem, the recommended dosage of DMG can range from 125 mg to more than 1000 mg daily. If you are dealing with a serious health problem, always be sure to consult with your health care practitioner.
Continued research with this nutrient will reveal even more about how DMG can be used effectively to combat the stresses and health problems that affect so many of us as we grow older. DMG can help you build wellness and live a more productive and healthier life.
  • Information
  • Ingredients/Directions
  • Further Reading
  • Health Uses
As many of you know, we have been out of stock of DMG for a while now, whilst wrangling over the name with customs in Asia. To them DMG sounded like it could be a restricted drug like DMA or DMH. We explained and provided documentation but they were simply unprepared to allow it. So, we have changed the name... nothing else, the ingredients are exactly as they always have been. It's not a change of name for marketing, just simply to ensure we can continue to supply the many of you who regularly use DMG 130 albeit under the new name of...
Multi Resolve & Boost (Energy & Immune System Formula)
The human body utilises DMG every day. It influences almost every cellular metabolic process so enhancing cellular metabolism and efficiency.
DMG produces a wide range of beneficial biological effects on the body including...
  • increased energy levels
  • improved neurological function and mental clarity
  • better physical performance
  • improved sexual function
  • better cardiovascular health
  • vastly improved immune system function, whilst inhibiting immune system response
  • better cholesterol, blood glucose and hormone levels
Research has found that DMG can enable one to function at improved mental and physical levels whilst simultaneously helping with the resolution of many diseases and health conditions.
DMG is truly an astounding nutritional supplement that I find myself recommending to everyone. I am sorry that I had not looked into DMG before, even though I took some briefly in the 1980's.
The reason I recommended it for everyone is that it tends to bring the whole system in to balance, so reducing the manifestation of diseases and health issues. Further, it adds a robustness to the system enabling it to cope with stresses of many types. An example of its incredible ability is that it is an extremely effective normaliser of the immune system; on the one hand boosting its efficiency and ability to keep disease at bay whilst at the same time reducing or eliminating auto-immune issues and tendency to inflammation.
These actions are achieved by significantly improving cell to cell communication and filling in gaps in the body's biochemistry (via methyl donation). Combined with its action of buffering stress as an extremely effective adaptogen, it can be useful even for those with adrenal fatigue and/or delicate health who struggle to find a therapy they can adapt to.
Many supplements have broad acting benefits, but the percentage of those using the supplement achieving significant boosts to their health is always limited by the body's ability to adapt and utilise it. DMG is not like those supplements, in as much as everybody should benefit from it's use. It is a stand out remedy in the advanced nutritional healing field, and personally I believe it should be included in any health nutritional program sooner or later.
John Claydon - Founder of Regenerative Nutrition

Natural Anti-Ageing Nutrient Boosts Strength, Stamina and Vitality

DMG has been the subject of clinical research since the early 1970's, over 40 years now. It has been shown to effectively improve the nutritional status of the whole body (cells, organs etc.) This enables one to function at more youthful levels no matter how old one might be.

Dr. Roger V. Kendall, Ph.D., author of Building Wellness With DMG, considers DMG as one of the most important nutritional supplements for health and well-being.

Dr. Roger V. Kendall, Ph.D., author of Building Wellness With DMG

Dr Kendall also maintains an interesting DMG website, please click here

Dr. James Balch, M.D., and Phyllis Balch, C.N.C., authors of the bestselling health book Prescription for Nutritional Healing recommend DMG for 48 different health conditions!

Writing in Prescription for Nutritional Healing:

N N Dimethylglycine Dmg

Dr. James Balch, M.D

N N-dimethylglycine For Cats

What have you heard about DMG?

Most people have heard little to nothing. Even the majority of MD's have no knowledge of it, being trained mainly as prescribers of pharmaceutical company products.

DMG is a catalyst for more than 40 crucial biochemical reactions in the body, all of which are linked to ageing. First discovered by Russian space programme scientists looking to resolve accelerated ageing in Russian cosmonauts, caused by exposure to ionizing radiation in space.

N N-dimethylglycine Dmg For Dogs

Russian cosmonauts returning from space missions, who had used DMG showed no symptoms of cellular damage and premature aging that the non-DMG-using cosmonauts all showed.

This ignited a huge interest in DMG within the Russian scientific community and researchers commenced studies into this nutrient on a scale that had never been seen before. These studies found that DMG acts at the cellular level and is necessary and vitally important in the production of amino acids, hormones, neurotransmitters, and DNA.

DMG has a powerful effect on the metabolism, enhancing metabolic processes such as cellular respiration, immune response, and oxygen utilization within the body.

These Russian scientists further realised that DMG is a prime component in the prevention of fatigue, in optimum brain function and in clarity of mind. DMG was also determined to be essential to the immune system's efficient functioning.

More recently, in 1990, a human study of the effects of DMG showed that it's use increased the production of antibodies within the body by more than 400%. [Reap EA, Lawson JW. (1990). Stimulation of the immune system response by dimethylglycine, a nontoxic metabolite. Journal of Laboratory and Clinical Medicine, 115, 481-486.]

The Foss Report on Nutritional Supplements states:

George Foss, Nutritional supplement expert, writing in his 'Foss Report on Nutritional Supplements”

A Return to Youthful Vitality... A Reality with DMG!

N N Dimethylglycine DmgDimethylglycine

After reviewing the research from the 1970's and the Russian space programme material, contemporary scientists like Roger V. Kendall, Ph.D. and soon, other researchers, undertook their own studies. These studies unveiled even more astonishing, new, benefits of DMG. These discoveries included the ability to help restore weakened immune system functioning, and to work as a cellular catalyst that makes the whole body work better.

Dr. Ray Sahelian, M.D., bestselling author of Mind Boosters: Improve Your Mind, Memory, and Mood

One reader of his book commented in an online forum......

I took 1,400 mg. of DMG by mistake (misread the directions). The most amazing thing happened. I built and installed a wall-to-wall laundry shelf, organized a laundry room and painted the room in one day. The reason I say this is amazing is because I've been in a couple of car accidents and suffered concussions. My brain has never been the same since. My typical day starts out with my hand on my cheek wondering what I'm supposed to do. Literally, I have to figure out what to do and how to do it, such as making a cup of tea, preparing a meal, feeding my dogs. Next I have to figure out what my responsibilities are for the day and how to do them. I have notes around the house to help me know what to do next. After taking DMG I felt like a super-human while building that shelf and giving the laundry room an overhaul. I knew exactly what to do. I was able to determine what tools I would need. I was able to determine exactly how to do the project. And I did the project with ease, excitement and with excellence. Not once did I experience those long frustrating pauses as to what I'm supposed to do and how to accomplish something.

So many DMG users now relate to this and find similar results.

How does DMG achieve it's Benefits

Dr. Roger V. Kendall, Ph.D. Is widely considered to be the world's leading expert in the biochemistry and therapeutic applications of DMG, he states that:

Dr. Roger V. Kendall, Ph.D., author of Building Wellness With DMG

Dimethylglycine

Jiashu Zhang, scientist, inventor and patent holder of a 'Method of producing N, N-dimethylglycine hydrochloride'

Other Medical CommentaryAbout DMG...

Many medical practitioners are opening up to the plethora of healing benefits offered by DMG

Cardiologist Dr. Mitchell Pries, M.D., Ph.D. has conducted many clinical trials on his patients since 1979. He has had overwhelming results with DMG supplementation. He says:

N N-dimethylglycine Hcl (dmg) Powder

Cardiologist Dr. Mitchell Pries, M.D., Ph.D.

Dr. C. Bartholomew of the Bluefield Clinic in West Virginia:

Dr. James Frackelton, M.D., of Cleveland, Ohio, treats cancer patients.

Dr. J. Noverini, D.C.:

Marina Zacharias, a holistic health practitioner from Jacksonville, OR

Dr.Passwater.com published a 2 part interview from 2003 - - To read both parts of the interview, please follow the 2 links below.

http://www.drpasswater.com/nutrition_library/Kendall_1.html
http://www.drpasswater.com/nutrition_library/Kendall_2.html



Dmg

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